Vol. 1 No. 1 (2026): October 2026 — Inaugural Issue

Research Papers

• Virtual Screening and Molecular Dynamics Prioritisation of Natural-Product NUDT1 Inhibitors for Colorectal Cancer

  Robyn Gerhard, Yidian Chu, Ananya Iyer (Author)

• Dual-Target Network Pharmacology of NUDT1 and CDK4 in Therapy-Resistant Non-Small-Cell Lung Cancer

  Chenxin Xu, Alec Aaron, Nattaporn Srisuk (Author)

• QSAR-Guided Optimisation of Benzimidazole Derivatives as Putative CDK4 Inhibitors in Pancreatic Ductal Adenocarcinoma

  Donia Obeidat, Myrto Georgantoni, Alyssa Amick (Author)

• Explainable Machine Learning for Prioritising Oxidative-Nucleotide and Cell-Cycle Targets in Ovarian Cancer

  Iya Maliki, Alireza Mohammadian, Valeria Hernández (Author)

• Systems Pharmacology of Metal–Benzimidazole Complexes in Triple-Negative Breast Cancer

  Isabella Papadopoulos, Angel Jaimes, Nicola Bell (Author)

• Multi-Omics Characterisation of NUDT1–CDK4 Co-Activation in Lung Adenocarcinoma and Its Association With Treatment Resistance

  Nikita Sitharam, Siu Wa Chui, Gabrielle Ndakwah (Author)

• Comparative Molecular Dynamics of Benzimidazole Scaffolds Against CDK4 and NUDT1: A Dual-Target Binding Study

  Ramya Shekhar, Hager Saleh, Millie Zhou (Author)

• Screening Saffron-Derived Apocarotenoids Against NUDT1 in Hepatocellular Carcinoma: An Integrated Computational Study

  Nethraa Kannan, Pernilla Siljehag, Hager Saleh (Author)

• Crocus sativus Petal Fraction Reduces Pain Behaviour and Oxidative Stress in a Murine Bone-Tumour Model

  Dhushanthi Keerthana Ramakrishnan, Rashidah Nakamyuka, Ifunanya Clara Agu (Author)

• Saffron-Derived Compounds as Adjuncts in Cancer-Related Inflammation and Pain: A Systematic Review and Meta-Analysis

  Ifunanya Clara Agu, Kara Barnao, Fan Yang (Author)

• Crocin as an Adjunct to Platinum-Based Therapy in Advanced Lung Cancer: A Double-Blind Pilot Randomised Trial

  Ruben van de Venter, Dineo Madikgetla (Author)

• Circulating 8-Oxo-dG, NUDT1 Expression and Saffron-Metabolite Exposure During Lung-Cancer Therapy: A Prospective Cohort Study

  Aditi Singh, Guoqing (Henry) Cheng, Ayaan Qureshi (Author)

• Dose–Response Analgesic and Anti-Inflammatory Effects of a De-Oiled Saffron Petal Fraction in Diabetic Neuropathic Pain

  Iya Maliki, Chenxin Xu (Author)

• Polarity-Directed Extraction and Metabolomic Profiling of Saffron Petals for Reproducible Anti-Inflammatory Activity

  Eric Neubauer Vickers, Devin Bowen Wan, Thembisa Monki (Author)

• Antimicrobial Activity of Neem and Bitter Gourd Extract Combinations Against Urban Respiratory Isolates

  Isaac Emmanuel Omara, Nabil Husni, Alissia Hui (Author)

• Urban Bioaerosol Exposure, Respiratory Symptoms and Household Use of Plant-Based Remedies: A Cross-Sectional Environmental Health Study

  Kara Barnao, Daniel Bergman, Rizky Pratama (Author)

• Hypertension, Diabetes and Severe Dengue in a Tertiary-Care Cohort: Interaction With Urban Exposure Indicators

  Mulualem Kelebie Admasu, Nethraa Kannan (Author)

• Prospective Validation of a Metabolic-Comorbidity Risk Score for Early Deterioration in Adult Dengue

  Susie Shuxin Xiao, Graeme Dor, Lina Carlsson Höglund (Author)